Friday 11 October 2019

What is Cannabicycloic Acid (CBLA)

CBLA is another precursor to another cannabinoid called cannabicyclol, which is a degenerative result of the addition of the other Phyto cannabinoid cannabichromenic acid (CBCA). When the CBLA is able to release carbon dioxide, it becomes CBL, and it’s another minor cannabinoid which is found in much lower concentrations. Right now, there isn’t a ton of therapeutic benefits that come with CBLA and CBC, but there is a suggestion that since it’s so similar to CBN in terms of structure, it might be anti-microbial, anti-inflammatory, and anti-tumoral in results, but right now, there still needs to be some confirmation. 

CBLA is not intoxicating, and it’s not psychoactive, so it’s something that doesn’t really affect the mind, and it also doesn’t interact with your cannabinoid receptors. This is not created directly through the use of cannabis and is something that does degrade when you expose the cannabis to heat that’s light, or UV light.  This is an interesting molecular formula, and it does become this after the decarboxylation of the CBLA in the compound. 

The potential Uses 

Right now, there is almost no research on the potential uses of CBL and CBLA, but right now, that’s pretty much where scientist are trying to go with this. It does pose a problem, as most research doesn’t look at the potential that this has, and it’s something that’s relatively rare, and is only found in certain concentrations, so in most cases, it’s hard to look at the effects of this. 

Right now, neither of these do offer affinity for both the CB1 and the CB2 receptors, and it doesn’t interact directly with your ECS. But it does combine with other terpenes, cannabinoids, along with flavonoids in order to create the entourage effect. 



It also is something that may be useful if you look at the therapeutic benefits of this. It does have a similar structure to CBN, which is another compound that has antimicrobial, anti-inflammatory, and antioxidant benefits that do come from this. 

Any potential side effects 

The thing is, because there is so little research, there is almost nothing on the effects that are there. Those that are decarboxylated are something that may possibly cause convulsions in some rabbits, especially at higher doses. However, the study of this was so small that they didn’t find anything that may pose a threat to humans in this, and this is something that’s a natural anticonvulsant in those who do have this. 

Strains that work 

CBLA is not a cannabinoid that you see in the wild a lot, so you’re not going to find any strain out there with super high concentrations of this. However, because it is a biproduct of the CBDA degradation, you might want to find some cultivars that are super high in both CBCA and CBC, which include the following: 

  • Blue Cadillac 

  • Blue cherry soda 

  • Maui dream 

  • Bubba cookies 

  • Purple candy 

Although this isn’t the biggest list, remember that this is something that does help to protect your plant from diseases and harmful UV rays that are out there, and it’s something that we don’t know much about what the cannabinoid in it of itself does directly to humans. 



Right now, it’s neither heads nor tales of whether or not it’s something that you should worry about using in humans, and it’s also something that can definitely be up in the air on benefits. 

For those who are curious about this, it’s important to look at the potential that this has, and to see for yourself, just what exactly this compound can do.


Thursday 6 September 2018

Medical Cannabis for Period Cramps

Period or menstrual cramps are a big problem for a lot of people, getting so bad that you need to use medication to get by. There are others who try medications, but the side effects somehow make it even worse. Some people have looked for solutions, but one that people are looking into is medical cannabis, and some may look at this as an alternative, since of course, it offers you a chance to have a more natural ingredient to treat these issues. 

Medical Cannabis Use 

Medical cannabis is becoming a whole lot more popular and is in fact, accepted as of late, being used to treat everything from cancer to MS, and even epilepsy, and there is even some evidence that claims it can help with chronic pain and other conditions too. With more and more states recognizing it, there are also a lot of parts to cannabis which help, including cannabinoids which help with improving your appetite, what you remember, and even pain and the movement issues you might have. it also works to help reduce nausea, pain, and other problems, with very little side effects too from it. 



Cannabis and Menstrual Pain 

These camps are caused by a hormone being released called prostaglandin within the lining, which causes cramps and spasms. This also does happen due to the lack of blood being pushed to the uterus too, and it can be unbearable for some people. It’s so bad for many that there is even a medical condition for this called dysmenorrhea, and right now, there is no solution for this. 



Painkillers are the most common prescription, but let’s face it, if you use them for too long, you can have a risk of addiction develop. If someone is dealing with this for a long period of time though, they could go years with this, and the painkillers also may cause other side effects too, including mood swings, fatigue and others. Cramps are not fun, but with marijuana, it can aid with this. This is because it can actually help target the endocannabinoid receptors, which are critical for slowing down this problem, making cycles a whole lot more manageable for many people. While it may not get rid of the period cramps right away, it can be helpful. 

Ways to Use it 

There are a variety of ways to use cannabis for menstrual cramps. One of the most popular, is smoking, due to the cannabinoids entering, helping with the pain, and with more and more people utilizing different ways to use this, you definitely can get relief for the short term. Another one is vaping, since it’s more discreet, and you’ll be able to also hide the odors from the cannabis product itself. 



It can be done with your own concentrates, or you can buy cartridges that you can just insert into the device in order to help with this. Edibles are another one, but it can sometimes take a lot longer. They’re effective though if you have long-term pain, and if you want to also just let the pain subside. You can have them in the form of anything from cookies to chocolate to even fruit chews. You can make your own or you can get them from a dispensary. 

Finally, a lot of people like to use cannabis for menstrual cramps in the form of topicals. You can rub this into the area affected and it does work pretty quickly. This is food if you need immediate relief from period cramps. Periods are painful but with cannabis, it can be more manageable. 

Tuesday 14 August 2018

Does CBD Oil Cause Insomnia

While CBD doesn’t usually case it, there are a few instances where it might occur. However, it actually usually does the opposite, giving you better, more restful sleep.  However, based on the doses, it can impact the sleep quality. Higher doses usually more sedative sleep. It can actually help some people get better sleep, since this is not a compound that’s psychoactive like how THC is. 

Insomnia is something that does cause problems for people, since there are sleep disturbances along with awakenings at night, where you get up and you’re unable to fall back to sleep. Anxiety, pain, depression, alcohol, and ecstasy and cocaine are some of the major causes of insomnia. However, CBD doesn’t actually cause it, but it does the opposite, since it can be hep with anxiety, depression, pain, and stressors too, and helps you improve your sleep functions better, resulting in sleep, which is more restful, and better for you. 



Why it might Create Insomnia 

There are some instances where yes, CBD does cause insomnia. 

The first, is the wake promoting. If you take low doses, usually around 15 mg or less in some cases, it’s more stimulating, and it negates those tired feelings.  Low doses of this compound as well improve the protein synthesis of the parts of your brain that are involved in waking up.  You also may feel like you’re starting to stay awake, rather than sleeping. However, this will not happen with larger doses 



Another reason is that you’re using it too much. If you use it every single night, it does create a tolerance in some people, so the body gets used to it, so your body won’t fall asleep with this. The way to combat this one, is to take larger dosages, however, it does create the problem where you need to have this in order to fall asleep, which creates a dependence on this, and it might result in you getting insomnia because of this. 

How to use this 

CBD does help with sleep because it can relieve pain, depression, and stress, and through the relieving of this, it can help with sleep, and even maintaining sleep.  Also, high doses of this is good for adults because it can help them get to sleep if they suffer from negative conditions which do directly impact this. 

If you’re going to use this, you want to make sure that you start low, and from there increase this and see what kinds of effects that this gives you. If you have sleep and anxiety troubles, you may want to start with a dose, see if it helps, and then start to increase this. 



About 160 mg of this is great for sleep, and it does increase the total amount of sleep and how often you’re waking up in the middle of the night. However, if you do need the sedative results from this, you should go for about 300-600 mg if you want to feel those effects and get a more deep sleep. 

In terms of when to take it, usually about a half hour to an hour before you go to bed is ideal, this is because it does need to be absorbed within the bloodstream before it works, and the impact does depend on how much you’re taking, your weight, and your own personal levels of metabolism

Overall though, if you take it as a tincture, it does work a little bit faster, and it can sometimes last a little bit longer and is slightly more potent.  The same thing can be said with smoking, as smoking usually is immediate.


Friday 5 January 2018

CBD For Autism

Autism, or autism spectrum disorder is a developmental issue that does prove to involve challenges with social situations, nonverbal communications, speech issues, and repetitive and restricted behaviors, with the effects varying. This is something that’s risen quite a lot in the last few decades for no reason, and right now, there is no cure for the condition too, but there are therapies and medications to make life as manageable as possible for the person. Some scientists are still looking at the different treatments, but one of the ways people treat autism conditions is CBD, which we’ll go over here. 

The Study 

There are some studies that show that CBD may be useful for this. That’s because it lowers their anxiety, helps with memories that are overstimulating, and aids with sleep, a common problem that many with autism struggle with.  When compared to the conventional treatments for this, it could be really helpful, as there isn’t’ really many good therapies for this. It’s something that has been studied too, and for some studies, it’s been found that for the 18 participants that tried this, there were positive results. CBD can help different autism conditions in a similar way that epilepsy patients benefit from this, and non-epileptic autism definitely benefits from this too. It can definitely be something that could help. 



The Improvements 

The study that involved 18 different patients with autism who utilized CBD products that were 3/.4 CBD and just a part of THC, and they were given capsules with this. It was found that in the patients it helped with a lot of other conditions typically associated with autism. Some of them include: 

  • ADHD symptoms 

  • Motor problems 

  • Communication problems 

  • Sleep disorders along with seizures 

  • Behavioral problems 

  • Issues with autonomy

  • Cognitive issues 

The biggest improvements definitely were in the sleep problems, social issues, and the seizures in these patients. Most of them did see improvement in at least one of the categories that were listed above. For a lot of people, these treatments may be a lot better than normal treatments. For a lot of people with autism, there are conventional treatments, and they come with huge side effects. It was also found that a lot of them did show benefit and a little bit less symptoms than normal. 



What About THC Though? 

This is another thing that some people wonder, since THC is psychoactive. This is the other cannabinoid that a lot of people look at. This actually can help, as it does bind to the same receptors, and also the anandamide that is there for those with ASD do have issues with behavior, and it can impact control. But THC can also help with this, and it could be a potential therapeutic benefit for those with autism. 

While it does work potentially, there is the anxiety factors to consider, as cannabis with THC in it can be a bit too overstimulating for those who suffer from ASD and have anxiety symptoms. But it may be a good thing. Is it a valid treatment? Both CBD and THC can be, and the studies are slowly coming forward on the benefits of both. 



For a lot of people, THC and CBD is something that can help with other effects, but for a lot with autism, it’s still something many struggle with. Because it’s such a diverse condition, it can be a bit hard to pinpoint whether or not it benefits a person with it. But, with more studies being done, we may see gross changes in autism treatment that help many people.

Monday 9 October 2017

Can Marijuana Be a Drug “Substitute”

This is something that’s been a major cause of interest in people. With drug addiction still running super strong, and millions people dealing with this, it’s definitely a burden of at least 1.5% of the entirety of the globe. With the debate about addiction still being something that’s there, with some being chemical, and others being an environmental approach, people are looking for solutions. 

Some people get relief through cold turkey quitting. Others benefit from going to rehab, and also getting less dangerous types of substitutes that are there. Some have explored the idea of using cannabis as a substitute, and it’s something that definitely could help for those who want something that is a good replacement for the more addictive options. Right now though, the results of this are quite unclear. 



Why Use Cannabis as A Substitute 

If you know a lot about cannabis, you probably also know that there isn’t a ton of human trials, and that’s because of the obvious. People are still afraid of cannabis, and they believe that even using this in a harmless, controlled setting will make things bad. But right now, there are some people providing the patients that they have with cannabis to replace different substances which are problematic, since there isn’t much evidence pointing to otherwise. 

However, with different research that harnesses the different subjective experiences, they learned to get some insights. It was something that was studied, and it was found as a way for people to use cannabis as a way to get off drugs that were harder. 



The study got a bunch of baby boomers around the bay area to answer some questions, offer audio recording, and they gave different responses on why they want to have cannabis. Some of the people said that cannabis is less about violent crime and helps with their bad tempers. Others say that it’s safer than other drugs. There are also other users who said that through cannabis substitution, they were able to get back to truly living life, and they definitely favored better compared to the more rigid people from rehab centers. This is an interesting piece of research, but does the science say otherwise? 

Does it help with Painkillers? 

It actually has. With opioids being some of the best painkillers out there, and they do work to reduce discomfort, they come with another problem, and that is addiction. They have a largely profound effect on your brain’s reward centers, and triggers the endorphin release, and it offers your body a chance to have better pleasures and a sense of being. However, this has lead to a big problem. That’s the opioid crisis that’s currently going on, which has led to a ton of addiction, and a ton of deaths, and about two thirds of fatalities out there come from this. And over 10 million older than 12 have misused this, as of recent. 



There are states that have legalized it, and have helped with treating these addictions, providing an alternative to different treatments, and less chance for abusing these substances. So yes, it can help.  It’s actually caused deaths to plummet by up to 25% in some cases, and it’s actually helped lower the deaths that are tried to opioid abuse, especially compared to marijuanaIt is something that can help, and it definitely can help with suppressing breathing as well.  It also can help to combat withdrawal as well, and some recent findings have offered a chance to prove this, so it might be something that is indeed, definitely possible with the right dosage. 

Thursday 17 August 2017

Cannabis for Chemotherapy Side Effects

Medical cannabis has been around for a long time, but one of the most important ways for it’s helped is for helping those with cancer. It’s actually great for a lot of people, especially for those who have chemotherapy-inducing nausea and vomiting. 

What is It? What’s the Treatment 

This is an overpowering and a debilitating condition, and it happens within the first 24 hours of a chemotherapy session. This is one of the most dreaded effects. It’s not just normal nausea, it’s so severe that it can be quite debilitating. Some people may use different anti-nausea medications and therapies, including corticosteroids, which help with treating this. 



But the problem with this is that the drugs may not work. It’s not something that works for everyone, and the thing is, even if you do activate this, a lot of people don’t actually respond well to this. They still feel lethargic, drugged, and delusional in some cases. Cannabis, however, is better for treating this, especially since there are now drugs with cannabinoids to help with this. 

How it works for Nausea 

The two most popular cannabinoid medicines, nabilone and dronabinol, block off the serotonin binding, and dopamine effects, which are both at the receptor sites of this.  This is something that controls the emetic reactions, so if you can target that, it can help to manage this. 



There is also the dorsal vagal complex near the brainstem which is responsible for the regulation of the emetic reactions as well, and it actually communicates the different responses within the blood. With cannabinoids, you can activate these receptors, reduce vomiting, and feel better. 

Cannabis and Nausea Treatments 

Many times, the cannabis works not just for CINV, but also all kinds of nausea. There’s even more evidence that shows that it can actually work better the more THC that’s in it.  Some strains that have this definitely work better than others, but ultimately, it depends on the concentration. The different ratios do offer varying effects of this. 



It’s also of note that CBD is good for this too, since CBD does activate the neurotransmitters, decreasing the nausea sensation, but there is more research needed to identify all of the dosages, the combinations, and the interactions of drugs that are used for nausea, and all other kinds of disorders and problems too. So if you’re someone with nausea, consider as well talking to a doctor to help with this, as they can prescribe certain medications to aid I the treatment of nausea in you, and make things so much easier as well. 

How to Start 

The best way to figure out if it’s right for you, is to  talk to a doctor. If you’re in a state where medical cannabis is legal, then just contract them, see if there is any way they can offer you a medical marijuana card and from there, get yourself some cannabis. Some people like edibles for nausea because they offer long-term benefits. However, they do take a bit longer, so if you’re feeling nausea that’s too much to handle, you may want something else. 

For a quick and easy relief, you can always get flower, a vape, or a sublingual means. All of these offer a fast way for you to get this in the bloodstream, and also to make this easier on you. For a lot of people dealing with cannabis, you definitely don’t want to miss out on this, and you should, with the doctor’s approval, get started on using this today, and from there, you’ll be able to, with this, get the benefits needed.


Tuesday 11 July 2017

Medical Cannabis Safety

With medical cannabis becoming a super popular means to get a variety of the health benefits that you want to, there are also now more claims about what types of benefits you get from this. You also may wonder if it can help with different symptoms. Since the discovery of the endocannabinoid receptors, it’s been found that both THC along with CBD do interact with this system. This is great, and THC can work to help with pain. but the problem with it, is that it’s still quite new, with more and more people wondering just what the symptoms and safety concerns are. Here, we’ll go over them, and what medical cannabis affects you should be worried about. 



The Uses of Cannabis 

So what can cannabis help with? Well, here are just a few of the symptoms that cannabis can help to alleviate: 

  • Anxiety, as this is something that can help ith mental health concerns, especially anxiety and other effects 

  • ADD and ADHD, since it helps a person focus without some of the side effects that come from this. 

  • Anorexia, which is a problem involving eating.  If you have this eating disorder, cannabis can help aid with this. 

  • Cancer, as this can help prevent or even slow down cancer, and there are now medications that contain this too. 

  • Pain, especially chronic pain. This can cause a lot of problems and be due to a ton of different conditions.  There are tons of medical cannabis products that help with this. 

  • Depression, as it can help to relieve this, making it easier for you. 

  • Seizures and epilepsy, as this is something that can be a major problem for people.  Some neurologists have recommended using cannabis oil with tons of CBD to help treat this. 

  • Nausea is another major problem that cannabis can help with, as it does relax the stomach and help the food stay don 

This is but a few of the different things that cannabis can help with. If you’re looking for new ways to get the help and treatment that you need, this is definitely something to consider. 

Side Effects and Safety 

Before the recent legalization of cannabis, some thought that marijuana was super dangerous. This is due to the reefer madness plague of the 1930s, here they thought that marijuana could cause this. However, after that, cannabis soon got outlawed, and is a schedule 1 drug, according to the federal government. However, with new studies, it is found that the new side effects are rare but not as serious as you would think they are. 



Some of them include: 

  • Paranoia 

  • Dry mouth 

  • Heart rate elevated 

  • Drowsiness 

  • Intoxication 

Long-term use is rare, but it may cause cannabinoid hyperemesis syndrome, but this is a rare condition here consuming cannabis does make you super sick. Also, as of note, both vaping and smoking also have a couple of downsides to the side effects, including breathing and lung issues, but it’s also still something that more and more people are actually looking to use other sorts of stuff. 



While there are a few side effects that come from consuming this, the side effects are almost nothing compared to the benefits that this has to offer, which is why more and more are turning to this kind of thing. 

If you’re curious about using this, then you’ll want to possibly talk to your doctor to learn a  bit about this to see if you’re able to qualify for medical cannabis usage, and other such things, and you’ll be glad that you did down the road.


What is Cannabicycloic Acid (CBLA)

CBLA is another precursor to another cannabinoid called cannabicyclol, which is a degenerative result of the addition of the other Phyto can...